Start with the construct
Review the expression host, construct status, induction strategy and target activity before defining feasibility work.
Host · construct · soluble activity
Discuss this application →
CONTRACT FERMENTATION · SCIENTIFIC & TECHNICALFrom expression.
Towards scale.
Enzyme expression and fermentation project enquiries. Define the host, activity target and recovery requirements for a scoped development programme.
Application-led selection
Controlled trials
Bulk enquiries
Technical support
START WITH THE APPLICATION
Enzyme Expression & Fermentation Development
for your process.
Enzyme expression and fermentation project enquiries. Define the host, activity target and recovery requirements for a scoped development programme.
Measure more than biomass
Discuss medium, feeding, induction, oxygen demand and foam control alongside enzyme activity and batch reproducibility.
Activity · growth · process conditions
Discuss this application →Plan the recovery
Define whether the target is whole cells, crude lysate or a recovered enzyme preparation, then agree the relevant quality measurements.
Harvest · recovery · retained activity
Discuss this application →A PRACTICAL ROUTE FORWARD
Enzyme selection.
Clear specifications.
Review candidate activities, required grade and documentation with our team. Ingredient supply, sample availability and any development work are agreed against your brief.
Project feasibility
Send the host, enzyme identity, existing results and target scale for an initial scope discussion.
Discuss this option →Development programme
Agree experimental design, samples, analytical methods, responsibilities and reporting before work starts.
Discuss this option →Scale-up planning
Specify the required enzyme format, batch acceptance criteria and supply objective. Capacity and facilities are confirmed in the quote.
Discuss this option →Tailored selection. Clear specifications.
Request a quotation ↗Tell us the application, required quantity and destination. Product availability, activity, grade, documentation and pricing are agreed in your quote.
DEFINE SUCCESS BEFORE THE TRIAL
Contract Fermentation trials.
Measured from the start.
Compare like with like. Agree the method, controls and decision criteria before scaling up.
DefineApplication, material and target specification
→SelectActivities, grade and operating conditions
→EvaluateRepresentative samples and suitable controls
→ReviewMeasured response and next-stage requirements
A USEFUL FIRST STEP
Start with a brief.
Build the evidence.
Initial project enquiries are welcome. Screening, formulation, testing and process development are paid services quoted to an agreed scope, with methods and deliverables defined before work starts.
Plan the next step ↗- Describe your application.
Host and construct, enzyme identity, induction system, available expression results, current scale, target activity, recovery format and required deliverables.
- Set the comparison.
Include the current process, control samples, operating conditions and analytical method.
- Agree the supply.
State the quantity, destination, documentation and intended project stage.
BEFORE YOU START
The details
that matter.
Can you accept every host or construct?
Host suitability, construct documentation, facilities and project requirements are reviewed before acceptance.
Is enzyme yield guaranteed?
Yield and soluble activity depend on the construct and process. Feasibility work establishes an evidence-based development route.
What does a quotation include?
An agreed experimental scope, responsibilities, measurements, reporting and commercial terms.
Do you offer bulk supply and tailored blends?
Send your application, required quantity, specifications and delivery destination. We will review a suitable supply or development route and provide a quotation.
APPLICATIONS. ENZYMES. EXPERTISE.
Scientific support.
From Oxford to your process.
Contract Fermentation is an application-focused website from Scientific and Technical Limited, based at John Eccles House, The Oxford Science Park, Oxford, UK. We support specification-led ingredient selection and application development enquiries.
Explore Scientific & Technical ↗LET’S TALK ABOUT YOUR APPLICATION
Discuss your
contract fermentation brief.
Send your brief for enzyme-selection support, sample availability or a commercial quotation.
sales@scientificandtechnical.com+44 (0)1223 626543